Too Good To Be True?
Nutrients Quiet the Unquiet Brain
A Four Generation Bipolar Odyssey
New information obtained after publication of
Good to be True? Nutrients Quiet the Unquiet Brain - A Four Generation Bipolar
July 5, 2014 On the Question of Lyme Persistence
This is a breakthrough of sorts, in spite of the
mixed messages in the article. A person considered a Lyme denier by many has
unwittingly admitted there may be a flaw in the Post Treatment Lyme Disease
Syndrome (PTLDS) argument that has prevented effective treatment for thousands
afflicted with Lyme disease. He writes, "It is unclear what mechanisms drive
this problem [of continued symptoms], and although slow or ineffective killing
of Borrelia burgdorferi has been suggested as an explanation, there is a
lack of evidence that viable organisms are present in PTLDS. Although not a
clinical surrogate, insight may be gained by examining stationary-phase in vitro
Borrelia burgdorferi persisters that survive treatment with the
antibiotics doxycycline and amoxicillin."
So, according to these authors, Lyme disease after
treatment is not due to active infection, but it might be worthwhile to assess
the problem of persistence. In my books, persistence means chronic.
"Persisting atypical and cystic forms of Borrelia burgdorferi and local
inflammation in Lyme neuroborreliosis". Looks like these folks have
some catching up to do. Wonder when they will begin to conceptualize chronic
Lyme and the immune system with so-called psychiatric diseases, MS and ALS.
October 9, 2012: Download free PDF preview from
Chapter 5 in Beyond Mental
The title of the chapter is "Perilous
Symbioses." The section is about GM foods. This preview is made available before
publication to inform readers on the issue of GM foods as they pertain to
California Proposition 37, the initiative to label GMO's.
July 30, 2009: The IDSA-ILADs face off: Does chronic lyme exist?
Read one person's summary of this
A Chimp and now a human becomes violent!
And still the IDSA closes its eyes and ears and wants us to do the same. Only
30 days to treat? Right! The church shooter who killed the pastor on Feb 8th,
2009 had Lyme disease previously documented in these articles.
Chimp shot by police after seriously injuring an adult
The chimp had Lyme disease, a fact that will likely not be pursued by the
Latest genetic discovery: two genes and bipolar disorder.
Each time breakthrough news comes out on genetics and bipolar disorder, there
is a sense of anticipation. Maybe this one will be the answer! As I am working
on my next book, Beyond Mental Illness I am becoming increasingly
convinced that there is no one cause or even causes of bipolar disorder (or
other mental disorders for that matter) because bipolar disorder is simply a
description of symptoms, not an actual disease. In my new book I refer to
it as bipolar syndrome in the say way that Tourettes is a syndrome, or, a set of
symptoms. If you have read my first book, you will know that my search for the
"holy grail" of a disease known as bipolar disorder was not successful. Instead,
I did identify some of the factors which combine to trigger the syndrome. Until
the diagnoses is at the level of those biological biomarkers, which are not the
same for everyone, the search for the cause of bipolar disorder will continue to
inspire hope followed by disappointment when the cure for the "disease" fails to
Giving vaccines to animals produces symptoms similar to autism
Autism is a disorder of the gut, not the head.
An article from March 22, 2007 issue of
Discovery Magazine supports a major point addressed in Too Good to be
True? Nutrients Quiet the Unquiet Brain. The innovations in treatment
brought on by the autism community are phenomenal and point to a model for
dealing with what we currently call mental disorders. Just as some
autistic children can be treated for identified triggers and no longer be
autistic, the same is true for bipolar disorder. However, mainstream medicine is
not yet willing to consider this possibility. You will be after you read this
Note the experimental use of an anti
inflammatory antibiotic minocycline discussed below for autism.
Lyme wars heat up.
An article entitled "Ticks aren't the only parasites living off patients in borreliosis-prone
areas" by David Wheland was published in Forbes Magazine Mar 12, 2007 (http://members.forbes.com/forbes/2007/0312/096.html).
The article is highly critical of Lyme Literate Physicians. Is this an new
salvo in an ongoing battle between the two camps discussed in the book? Is
it a defensive response to Connecticut Attorney General Blumenthal's
investigation into the possible anti competitive activities of the Infectious
Disease Society (IDS)? The IDS guidelines minimize the seriousness of Lyme
disease, especially chronic Lyme. Meanwhile, we have the International
Lyme and Associated Disease Society (ILADS) coming out with their own treatment
guidelines supported by a considerable body of scientific evidence; we have
investigations into the practices of Lyme Literate Physicians one of whom,
Dr Charles Jones, has treated 7,000 children with Lyme disease over the
years, saving many lives in the process. As I stated in the book, I am not
qualified to assess the scientific merits of both sides, though I clearly have
my own evolving views. Readers are encouraged to do their own due
diligence. Here is an interesting perspective.
In 1880 former managing
editor at the New York Times John Swinton had this to say about the free press.
"There is no such
thing, at this date of the world’s history, in America, as an independent press.
You know it and I know it. There is not one of you who dares
to write your honest opinions, and if you did, you know beforehand that it would
never appear in print. I am paid weekly for keeping my honest opinion out of the
paper I am connected with. Others of you are paid similar salaries for similar
things, and any of you who would be so foolish as to write honest opinions would
be out on the streets looking for another job. If I allowed my honest opinions
to appear in one issue of my paper, before twenty-four hours my occupation would
The business of the journalists is
to destroy the truth, to lie outright, to pervert, to vilify, to fawn at the
feet of mammon, and to sell his country and his race for his daily bread. You
know it and I know it, and what folly is this toasting an independent press?
We are the tools and vassals of rich men behind the scenes. We are the jumping
jacks, they pull the strings and we dance. Our talents, our possibilities and
our lives are all the property of other men. We are intellectual prostitutes."
For a balanced discussion of this
controversy visit a recent
Columbia Magazine article featuring Dr. Brian Fallon whose ground breaking
research on long term antibiotic treatment of Lyme disease will soon be
Possible antipsychotic effects of minocycline in patients with
Researchers discuss two patients exhibiting symptoms of what is generally
called schizophrenia who responded favorable to minocycline, an antibiotic that
crosses the blood brain barrier. Whether the effect is due to the
antibiotic effect or neuroprotective effects is uncertain.
Miyaoka T, Yasukawa R, Yasuda H, Hayashida M, Inagaki T, Horiguchi J.
Department of Psychiatry, Shimane University School of Medicine, 89-1
Enyacho, Izumo 693-8501, Japan .Prog Neuropsychopharmacol Biol Psychiatry, Oct
4, . 2006
The Two - Minute 24 - Hour Mania Manager.
An article written by the author is published in the July 2006 issue of the
Townsend Letter. The article explains the theory behind the use of left caloric
vestibular stimulation to stop mania almost instantly and describes the
successful use of it with two cases.
A Must Read!
Autumn Stringam, whose father helped develop E.M. Power has now published a
book entitled These Painted Wings. This is a moving account of her
family's history, a central them of which is that paradoxically, her mother's
death by suicide started a chain of events that brought life and health to
thousands of others. It is a simple, touching and wonderful story. Autumn was
psychotic and symptomatic on and off drugs; she took the supplements, got off
all drugs, and she has been symptom free for years, even bearing healthy
children when doctors had advised against it. Readers should bear in mind that
bipolar disorder is a constellation of disorders and that while E.M.Power is
effective for many, when other risk factors are causing the symptoms a
nutritional approach may not be sufficient and could be excessively risky. This
is why professional consultation is recommended before anyone changes their
treatment program. The book is no longer available but will be published
this fall by a major book publisher under the title "A Promise of Hope."
The role of intracellular parasites in
schizophrenia; the effectiveness of antibiotics and immunotherapy for
The evidence continues to trickle in. B. Fellerhoff and others from the Institute
of Immunology in Munich Germany have written ground breaking articles in
Medical Hypothesis and The Journal of Molecular Psychiatry confirming that infections can and do play a role in psychosis.
They found chlamydial infections in 40.3% of the schizophrenic patients compared
to 6.7% of a healthy control group. Treatment consisted not only of
antibiotics but also immunotherapy which they found was restorative
without the use of antipsychotic drugs. In addition, they found a
particular genetic vulnerability as well. Google on "fellerhoff +
schizophrenia" or search for articles on PubMed.
Incidentally, C. Pneumonia is also
associated with some cases of MS, aneurysms and stroke, suggesting that
current symptom based diagnoses for any number of disorders, including CNS
disorders do not reflect the heterogeneity of actual disease processes that produce the symptoms
which lead to the labels.
Anti TNF medications and and
A May 17 07 article in JAMA entitled Anti-TNF Antibody Therapy in Rheumatoid
Arthritis and the Risk of Serious
Infections and Malignancies found that tumor necrosis factor (TNF) is important for defense and tumor
growth control. The review of the literature suggests that anti-TNF antibody
therapies may increase the risk of serious infections and malignancies. The odds
ration for malignancy was 3.3, for serious infection 2.0. Higher doses of anti-TNF
medications resulted in greater risk of malignancy. In the book and in a study
discussed below I discussed the role of anti-TNF medications in schizophrenia.
While they are effective in reducing symptoms, presumably by mediating the
effects of certain immune responses, it appears that either a targeted treatment
of specific cytokines or successful treatment of the infection would be
preferable than increasing risks of further illness or tumors. It will be
interesting to see how researchers in the future will explain the documented
positive relationship between rheumatoid arthritis and cancer patients and the
inverse relationship between rheumatoid arthritis and schizophrenia. The answers
may lie in the area of the immune response to infections.
Anecdotal stories about EMPower
Some very dramatic "too good to be true" anecdotal stories are being shared
from the Truehope offices. For example, there was a elderly man who was
severely brain damaged after a stroke and a fall where he hit his head. After 14
months he still could not walk or feed himself. He talked with a slur. After
taking E.M. Power for an unknown period of time he could walk, feed
himself, and talk without a slur. There is the woman who had been in a
wheelchair with MS I discuss in the book. There was a man with a treatment
resistant case of psoriasis whose skin cleared completely on a new more potent
formula of E. M. Power that will be coming out soon. If one considers MS,
psoriasis and bipolar disorders as a consequence of immune processes run amok, then the supplements
must help the body's immune system to respond more appropriately to whatever it
is that is provoking an antigenic response. These anecdotal stories do not
prove anything but they are certainly interesting, and, since a state of inadequate
nutrition predisposes the body to illness and disease it would seem only logical
that a state of
sufficient nutrition would prevent illness. Click
here for a transcript of the 38th Canadian Parliament standing Committee on
Health in which regulation of Truehope and similar products is discussed.
The Marshall Protocol - a new breakthrough?
According the Dr Marshall, who
developed the Marshall Protocol, feedback from patients with dementia, MS,
Sarcoidosis and Lyme disease is very positive. While the protocol
developed out of Dr Marshall's research on Sarcoidosis , it
actually applies to what he calls chronic cell wall deficient infections that
reside in phagocytes and yet cause cytokine cascades. He uses very small amounts
of antibiotics with Benicar which binds with enzymes essential for these
bacteria to create proteins. No one has yet applied his ideas to the treatment
of "psychiatric" disorders primarily because very few psychiatrists understand
the relationship that often exists between Lyme and other infections and
psychoses. His protocol is not just for Lyme disease but for any number of
bacteria and mycoplasma that the phagocytes are unable to recognize and destroy.
The bugs have evolved a way to stealthily live in the very phagocytes that would
destroy them. As I recently stated on MMI, large doses of antibiotics for
Lyme is tantamount to a tank blasting away while the Marshall Protocol is like a
sniper targeting in on the specific enemy. Research discussed in the
book showing an increased risk for major psychiatric disorders to adult children
of mothers who had antibodies to herpes simplex virus type 2 during their
pregnancy may be consistent with Dr Marshall's ideas. Positive results for MS have been reported
through both nutritional
supplementation and targeted treatment of cell wall deficient bacteria. Dr
Marshall is not a physician. His doctorate is in an unrelated field. Like Geoge
Eby in the book, he had to find a cure. He had sarcoidosis, he cured himself,
and now his Marshall Protocol is being used all over the country with apparent
great success. His work runs counter to many established studies on the
effectiveness of Vitamin D for the prevention of numerous illness and is
6,000 to die this year from QT-c-prolonging medications ? (including
intestinal medications and antipsychotics)
The quote says it all: "Although prolongation of the QTc interval by
non-cardiac drugs is not an unusual finding, potentially fatal arrhythmias and
sudden cardiac death are relatively uncommon," Dr. Stricker said. "Nevertheless,
our results suggest that 320 cases a year of sudden cardiac death can be
attributed to QTc-prolonging medication in the Netherlands and, by
extrapolation, around 9,000 in Europe and 6,000 [in] the USA."
Eur Heart J. Posted
online May 11, 2005. You will need to sign up for access to Medscape. It is
article features EMPowerplus
Discover Magazine includes comprehensive essay on EMPowerplus, the latest
product from Truehope. (http://www.discover.com/issues/may-05/features/vitamin-cure/?page=1)
Brian Nichols - An example of san paku
(March 13, 2005) Ashley Smith, in describing her harrowing ordeal with 33
year old Brian Nichols who allegedly killed four in Atlanta, commented in a
dramatic televised interview that at one point he told her he should be shot in
the back of the head. According to her, he said to her, " I am dead already. Look at my eyes. "
In the mug shot his eyes look very similar to those of Mohamed Atta and Margaret
Jones discussed in the book.
Lyme Disease can play a role in 300 chronic illnesses!
Dr. Lee Cowden from Dallas Texas discussed this statistic December 5th,
Cary Nosler's Wide World of Health. At the link below you can find studies
showing involvement of Lyme with these illnesses. Examples include bipolar
disorder, schizophrenia, MS, ALS, Alzheimers, heart block and stiff person
syndrome. I find the link with stiff person syndrome particularly
intriguing since in the book I discuss similarities between what I call "mania
of the cerebrum" and "mania of the cerebellum." This is not to suggest
that all these conditions are solely caused by Lyme disease, but rather that
Lyme can trigger or cause these conditions. This link does not imply endorsement
of any products. While some have claimed great benefit from Samento, and the
site discusses one study that seems too good to be true, doctors with whom I
have talked have not been able to replicate the results. Indeed, some report no
progress and even adverse effects. On the other hand, these physicians did not
do the comprehensive protocol that Dr Cowden did, of which Samento was only one
part. Unfortunately there is as of yet no "magic"
drug or remedy that will cure Lyme disease.
http://www.samento.com.ec/nutranews/story002.htm The "kitchen sink" approach
appears to be the most effective but there is still debate on which parts of the
kitchen sink are needed. For the Alzheimer connection go to
Folic Acid Enhances Repair Processes in the Adult CNS: Animal Study
This study supports the notion that in adult rats, folic acid supplementation
aids in the growth, repair and recovery of central nervous system (CNS) injury.
To access the site below registration at Medscape is required.
Reuters Health Information 2004
Historic Discovery: Mania can be stopped in two
minutes for up to 24 hours. The technique is more effective than Zyprexa or ECT!
And, it is an accepted medical procedure already practiced by neurologists,
though not currently for mania.
A psychiatrist from New Zealand, Dr. Mike Dodson, has clinically
confirmed Dr Jack Pettigrew's slow switch theory of bipolar disorder
discussed in the chapter entitled "Switches, Widgets and Brain Cells."
Details in the book.
Nutrients restore brain tissue!
exciting research from the U of Lethbridge shows that nutrients actually
restore damaged brain tissue. Two groups of rats were given a regular diet
or a diet supplemented with E.M. Power or inositol alone. The offspring of
these rats had parts of their brains removed at birth. Those offspring fed E.M. power
(from the mothers fed E.M. Power) performed much better than those fed regular diet. Their brains
suggesting that the nutrients facilitated new brain growth. Rats fed only
inositol also did better, but their improvement was not as broad based as
with E.M. Power. They are now examining whether E.M. Power could be effective
in rats who have had a stroke. Double Click here to download 2.6 meg Powerpoint poster presentation. In my (back yard mechanic's) opinion,
this study suggests that
brain repair, not "brain interuptases" is where the focus needs to be.
Note: Infant rats can grow new neurons given proper nutrient support.
There is no evidence that adult humans can grow new neurons except that the
dendritic branches of the neurons may expand.
"Diet can stimulate functional recovery and cerebral plasticity after perinatal cortical injury in rats," Celeste Halliwell and Bryan Kolb from
the Canadian Centre for Behavioural Neuroscience, The University of
LethbridgePublication is pending in the
Neuroscience Abstracts, 2003, vol 28, 459.11
Nutrients change genetic expression of proteins in mice.
Another study at Duke University
showed that four basic nutrients, vitamin B12, folic acid, choline
and betaine can change genetic expression
of proteins in mice. The mice genetically bred
to producing offspring with yellow fur and diabetes produced offspring without yellow fur or diabetes. To me these are marvelous examples of a
marriage of nature and nurture. Genetic expression of proteins is
altered by nutrients. The process involves methylation. While
the implications need to be thoroughly researched, if this work is
replicated it would suggest that those who carry genetic risks may
improve their odds of having a normal baby with the right supplementation
for mother and baby. If nutrients can change genetic expression or proteins
for the better, might it be possible that lack of nutrients over time might
likewise alter genetic expression of proteins for the worse?
http://www.futurepundit.com/archives/001692.html The article is in the
Aug. 1, 2003, issue of Molecular and Cellular Biology
Supplements as good as Ritalin, study shows
Charles Gant M.D., Ph.D.and Karen Harding, Psy.D., R.N. co-authored an article
in the August 2003 issue of Alternative Medicine Review. They tested ten ADHD
children on Ritalin and ten treated with a broad-scale nutritional supplements
(Nutrenergy products). Both groups performed equally well in post testing.
An epidemiological overlap between rates of schizophrenia and multiple
Thanks to MMI
poster Jutta Zacharias, I recently learned of this article that was published
in December 2002. Some amazing epidemiological facts: There is a "striking
epidemiological overlap" between rates of schizophrenia and multiple
sclerosis. As people from warm climates migrate to colder northern
climates their rates of MS and schizophrenia increase. Without going into all
the details the bottom line is that rates of infection of Lyme appear related
to rates of MS and schizophrenia. Go to the site listed below to read more
about this. By the way, MS patients also have twice the rate of bipolar
disorder as a healthy population.
August, 2003 "Geographical and seasonal correlation of multiple sclerosis to sporadic
Fritzsche," International Journal
of Health Geographics 2002 1:5 Clinic for Internal Medicine, Soodstrasse 13,
8134 Adliswil, Switzerland
May, 2003 "'Lyme disease': ancient engine of an unrecognized
This seminal article published this May in Medical Hypotheses (Med
Hypotheses. 2003 May;60(5):742-59) is simply staggering in its implications.
The central premise is this. Lyme disease as we know it is restricted to a
narrow definition provided by the CDC that does not take into account the
world wide epidemic of borreliosis that has occurred for ages and which has
been passed down through innumerable generations through such mechanisms as
sex, and breast feeding. The authors state, "We
conclude that 'Lyme disease' currently acknowledges only its zoonosis arm and
is a limited conceptualization of a far more pervasive and unrecognized
infection state that must be considered a global epidemic."
This broad perspective helps to explain some
unresolved issues in the book.
The study discussed in Too Good to be True?
Nutrients Quiet the Unquiet Brain that reported increased antibodies to
Lyme disease in psychiatric patients raises more questions than it answers.
Does this mean that psychiatric patients enjoy the outdoors more - in tick
infested areas? Very unlikely. Does it mean, as one psychiatrist suggested to
me, that the mentally ill are homeless and therefore outdoors more where they
are exposed to ticks? Hardly. In the light of the above the answer may be
that those patients who have a genetic predisposition to experience symptoms
in response to this infection may simply have had borreliosis passed on
through their families, and that such intergenerational transfer has occurred
for eons, not just from the 1980's when certain youth in Old Lyme Connecticut began
to experience arthritis and other symptoms from tick bites.
These findings would suggest that the
exploration of the role of Lyme in psychiatric disorders in Too Good to be
True? Nutrients Quiet the Unquiet Brain only only explored the tip of the
iceberg. Given that a Dr Gregory Bach found Lyme disease in 40 patients
diagnosed with ALS and cured two of
them by treating their Lyme disease, this is an area that needs needs
Doctors W T. Harvey and P. Salvato
meticulously document the limitations of our current understanding of Lyme
disease. They find no other way to explain the positive symptoms and lab
findings in their patients in Houston, an area where the typical carriers such
as are found in the North East apparently do not exist.
Milk and Diabetes - a prototype of milk and psychiatric disorders?
Here is a summary of some
interesting research from the December 1999 Townsend Letter that
complements material in Too Good to be True. There are several genetic
variations in cows milk. While across the board consumption of milk does not
correlate with increased diabetes, certain of the variants yield a pronounced
relationship between intake and diabetes (p = 0.0001) Just as humans have
particular genetic alterations (haplotypes) that predispose to chemical, mold and Lyme sensitivity,
apparently cows have genetic variability that affects the proteins in their
milk. If particular proteins in particular cow's milk predispose to diabetes, then perhaps some but not all milk causes brain
antibodies that predispose to psychiatric disorders. Perhaps in the
future, customers will be able to identify and avoid the particular variant that
would have predisposed to either diabetes or psychiatric illness. In the
meantime, casein (and gluten) can be harmful to psychiatric patients. (Editorial implications
Elliot, R.B., et. al. Type I (insulin-dependent) diabetes
mellitus and cow milk: casein variant consumption., Diabetologia, 1999;
Bartonella and Psychosis?
Mar 6, 2003 -
Who would have thought that the apparently innocuous cat scratch disease, an
illness that waited 50 years for a definitive cause (Bartonella) could prove
to be so devastating to those with compromised immune systems? This UCLA study
found that 50% of AIDS patients (numbers unknown) with psychosis have Cerebral
Spinal Fluid (CSF) with
Bartonella antibodies while none of the AIDS patients without psychosis had
any Bartonella antibodies in their CSF. Correlation is not causation, but this
relationship bears further investigation, particularly so with Lyme patients.
Given that Lyme patients are often immunocompromised as evidenced, for
example, by low levels of natural killer subset (CD57+), there are significant
implications for Lyme patients that need to be researched. For more
information go to the following URL and scroll down to "Bartonella
henslae and AIDS-related Psychosis."
Celebrex and Schizophrenia
Mar 8, 2003 - In the book I discuss pending
research through the Stanley Foundation to explore the efficacy of cytokine
(e.g. Tumor Necrosis Factor) binding products such as Enbrel in
schizophrenia. If cytokine proliferation secondary to exposure to viruses or other antigens
were responsible for some of the symptoms of schizophrenia, then these
products might be therapeutic by binding with these cytokines (See Chapter
19, "Cytokines - Too Much of a Good Thing"). While I have found no evidence
of the results of the Enbrel study, there has been a study involving Celebrex, a similar cytokine binding drug. Schizophrenic patients given
Risperdal and Celebrex did significantly better than Risperdal alone. This is a very preliminary study and there is no proof that cytokine binding effects were the cause, but it is a surprising finding that may lend support to the notion that chronic infections and the body's immune response to them may play a significant role in mental illness.
Fourth Study Published on Nutritional
Mar 21, 2003 - This particular study
published in March 2003 in the Journal of Clinical Psychiatry
describes how one psychiatrist, Dr. Miles Simmons,
used nutritional supplements in his practice with bipolar patients. The
paper states that 11 of 19 patients were able to stay on the supplements and
did not need psychotropic medications for an average of 13 months. Four
discontinued the supplements because of gastrointestinal problems and one
was lost to follow-up. Three had recurrent symptoms and had to
start taking psychotropic medications again.